Folic acid and other vitamins B help break down homocysteine, an amino acid in the blood. High levels of homocysteine are associated with increased risk of heart disease.
For this reason, some scientists speculated that folic acid supplements can reduce homocysteine levels, which, in turn, can reduce heart disease risk. But new research shows that lowering homocysteine in this way has no effect on preventing heart attacks. Conversely, it may even increase slightly the risk of triggering a heart attack.
Also, the cumulative evidence indicates that dietary folic acid can reduce stroke risk. Reduction of stroke was observed to speculate because the pulse pressure drops produced by folate supplementation of 5 mg per day, because hypertension is a major risk factor for stroke just review shows that in some individual stroke risk seems to be reduced, but definite recommendation regarding supplementation beyond the daily allowance currently recommended for stroke prevention has not been defined.
Two independent research conducted by the researchers concluded that combined daily administration of 2.5 mg [milligrams] of folic acid, 50 mg of vitamin B6, and 1 mg vitamin B12 for five years had no beneficial effect on major cardiovascular events in high-risk population with heart disease.
However, a consultant for Nutrition Board is responsible, said the findings may not apply to relatively healthy Americans, because the two study populations involved ill individuals with a history of heart attack, heart disease, diabetes and other problems.
However, the American Heart Association (AHA) does not recommend the use of folic acid supplements by the general public to reduce the risk of heart disease.
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